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Cancer vax combo keeps dazzling
Posted 22 January 2026 AM
Striking new data shows that Moderna's cancer vaccine in combination with MSD's Keytruda continued to halve the death rate for patients with resected high-risk melanoma, even after five years.
The companies announced "sustained improvement" in the primary endpoint of recurrence-free survival from the Phase 2b KEYNOTE-942/mRNA-4157-P201 study evaluating intismeran autogene (mRNA-4157 or V940), an investigational mRNA-based individualised neoantigen therapy, in combination with Keytruda in patients with stage III/IV melanoma following resection.
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Posted 22 January 2026 AM
Striking new data shows that Moderna's cancer vaccine in combination with MSD's Keytruda continued to halve the death rate for patients with resected high-risk melanoma, even after five years.
The companies announced "sustained improvement" in the primary endpoint of recurrence-free survival from the Phase 2b KEYNOTE-942/mRNA-4157-P201 study evaluating intismeran autogene (mRNA-4157 or V940), an investigational mRNA-based individualised neoantigen therapy, in combination with Keytruda in patients with stage III/IV melanoma following resection.
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