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MSD drops $16b into IBD fight

Posted 18 April 2023 AM

MSD is making a $16 billion bid to boost its autoimmune pipeline with a promising candidate for ulcerative colitis and Crohn's disease, making an offer for NASDAQ-listed Prometheus Biosciences.

The main target is the TL1A inhibitor, PRA023. Prometheus announced extremely promising results from Phase 2 studies last year, which targeted moderate to severely active ulcerative colitis and moderate to severe Crohn's disease. It is also in Phase 2 trials for systemic scleroderma interstitial lung disease.

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