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Saturday, 14 December 2024
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New niche for checkpoint drugs

Posted 18 March 2024 AM

An Australian-led study has uncovered a potential new approach to checkpoint inhibitor (CPI) therapy in bladder cancer.

The first-in-human trial conducted by the Australian and New Zealand Urogenital and Prostate Cancer Trials Group (ANZUP) assessed sub-urothelial injection of AstraZeneca's PD-L1 inhibitor Imfinzi in 11 patients with non-metastatic muscle-invasive bladder cancer (MIBC) who hadn't received chemotherapy or immunotherapy before.

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