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Posted 28 October 2025 AM
Novartis is strengthening its neuromuscular portfolio with an $18.4 billion (US$12 billion) acquisition of Avidity Biosciences for its next-generation antibody-oligonucleotide conjugates.
It's the second largest pharma acquisition of the year, just behind J&J's purchase of Intra-Cellular Therapies in January. The deal gives Novartis three potential first-in-class late-stage clinical assets targeting neuromuscular diseases by linking various oligonucleotides to muscle-specific antibodies (AOCs). The merger is expected to close in the first half of 2026.

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